Hmmm. I didn't need to mess around with any bin files.
But I did have a similar issue... When I did apply the brakes and come to a full-stop then switched direction, I did notice that sometimes the engine would just rev and not move when I put up the throttle a bit. It's like the train was "stuck" in place.
Then, when in-cab view, in noticed there are two separate brakes I found, the "AutoBrake" and the "Independent Brake".
Releasing the brake using the F4 Driver's HUD sometimes only seemed to release the "AutoBrake", but sometimes the "Independent Brake" stayed on.
When this happened, from in-cab view I had to grab and manually move the "Independent Brake" lever all the way to the left to release it, then when I applied a bit of throttle I was able to go in the opposite direction as I wanted then.

"AutoBrake" is the big brown-handle looking lever. The "Independent Brake" is the smaller black-handle looking lever underneath.
Don't know if this was the same issue you guys were having, but it worked for me.