Railworks America

This site has historical maps for all of Pennsylvania's counties. Could come in handy:

http://www.dot.state.pa.us/Internet/Bur ... CountyMaps

Do you also know of a site that has old building blueprints from Pennsylvania.

Those would defiantly be useful to me and then I'd build some of the buildings for Railworks.

As far as building a route, I can't read a map like this for anything, or even know of how to set it up.

Check this resource, it has all you need: The Library of Congress, especially the H.A.E.R. collection, I can browse that for hours!
http://www.loc.gov/pictures/collection/hh/

Would you care to do Thurmond, W.Va. for instance?
You can find detailed drawing like these and many more, ready to model:


Or historic Cleveland, Pittsburgh or any other major US city that has a university with a history department and electronic library.
Pay special attention to the rapidly vanishing public and civic architecture from the 20's till 40's in Art Deco style.